Sadio Mane tormented Chelsea as the Liverpool forward struck twice after sparking Andreas Christensen's dismissal in the champions' 2-0 win, while Son Heung-min scored four as Tottenham crushed Southampton 5-2 on Sunday.
Mane was involved in the turning point at Stamford Bridge as the first clash between Premier League title contenders this season swung Liverpool's way.In first half stoppage-time, Jordan Henderson picked out Mane's run behind Christensen and the Denmark defender responded by rugby-tackling the Senegal star to the ground.
Referee Paul Tierney initially booked Christensen, but VAR told him to consult the pitchside monitor and he changed his decision to a red card.
Mane grabbed his first goal of the season in the 50th minute as he met Roberto Firmino's cross with a thumping header after eluding Reece James' slack marking.
Mane was gifted his second goal as Chelsea keeper Kepa Arrizabalaga made a hash of trying to play out from the back, allowing the Liverpool forward to intercept and slot into the empty net.