Hamas is open to an agreement to end the war in Gaza that would see all hostages released and secure a five-year truce, an official said Saturday ahead of talks with mediators.

A Hamas delegation was in Cairo to discuss with Egyptian mediators ways out of the 18-month war, as on the ground rescuers said an Israeli strike on a family home in Gaza City killed at least 10 people and left more feared buried under the rubble.

The Hamas official, speaking to AFP on condition of anonymity, said the Palestinian militant group "is ready for an exchange of prisoners in a single batch and a truce for five years".

Meanwhile, Gaza's civil defence agency said Israeli strikes on Saturday killed at least 17 people across the territory, while more trapped under the rubble after a family home was hit.          

Israel resumed its military campaign in the Gaza Strip on March 18, ending a two-month truce that had largely halted the fighting.

"Israeli air strikes in several areas killed 17 people since dawn," civil defence official Mohammed Al-Mughayyir told AFP.

A strike on the house of Al-Khour family in Gaza City's Sabra neighbourhood killed 10 people, Mughayyir said, with witnesses reporting an estimated 20 victims trapped beneath the rubble.

Mahmud Bassal, spokesman for the civil defence agency, had earlier said that about 30 people were missing under the rubble.

The UN's World Food Programme said Friday it had depleted its food stocks in war-ravaged Gaza, where Israel has blocked all aid for more than seven weeks.

WFP, one of the main providers of food assistance in the Palestinian territory, said it had "delivered its last remaining food stocks to hot meals kitchens in the Gaza Strip" on Friday.

It said "these kitchens are expected to fully run out of food in the coming days".

The World Health Organization chief warned Friday that medical supplies were running out in Gaza, insisting that Israel's aid blockade of the war-torn Palestinian territory "must end".

After the World Food Programme said that its stocks had depleted in Gaza, where Israel has blocked all aid for more than seven weeks, WHO chief Tedros Adhanom Ghebreyesus warned on X that "the situation is the same with medical supplies. They are running out", insisting: "This aid blockade must end. Lives depend on it."

The head of the UN agency for Palestinian refugees on Friday condemned Israel's more than seven week aid block on war-ravaged Gaza as "a man-made and politically motivated starvation".

"The Government of Israel continues to block the entry of food + other basics," Philippe Lazzarini wrote on X.