Toby Alderweireld gave Tottenham a late 2-1 win over Arsenal as Jose Mourinho's men climbed above their north London rivals, while Bournemouth kept their survival hopes alive with a chaotic 4-1 victory against Leicester on Sunday.
Mourinho had endured a barrage of criticism as Tottenham slipped out of the race to qualify for the Champions League with just one win in three games.But thanks to Alderweireld's winner with nine minutes left, Tottenham took the local bragging rights and got back in contention for a place in next season's Europa League.
Tottenham are eighth, two points above ninth placed Arsenal and two behind Sheffield United as they try to avoid missing out on European action for the first time since 2009-10.
In the first north London derby at the new Tottenham Hotspur Stadium, Alexandre Lacazette put Arsenal ahead in the 16th minute with a stunning long-range strike.
Arsenal's lead lasted just three minutes as Sead Kolasinac's sloppy pass was intercepted by Son Heung-min, who eluded David Luiz before chipping over Emiliano Martinez.