Pakistan captain Babar Azam won the toss and sent New Zealand in to bat Monday in the first day-night international in Karachi.
Pakistan handed an ODI cap to 27-year-old leg-spinner Usama Mir after showing good form in domestic matches, while New Zealand included all-rounder Henry Shipley, 26, for his first international.
New Zealand, runners-up at the last World Cup in 2019, won 10 of their 16 ODIs last year.
They have been dominant against Pakistan, having won 12 of the last 15 ODIs between the two teams.
The 2023 World Cup is set for India later this year.
New Zealand: Kane Williamson (captain), Devon Conway, Finn Allen, Daryl Mitchell, Tom Latham, Glenn Phillips, Michael Bracewell, Mitchell Santner, Henry Shipley, Tim Southee, Lockie Ferguson
Umpire: Aleem Dar (PAK) and Asif Yaqoob (PAK)
Tv umpire: Ahsan Raza (PAK)
Match referee: David Boon (AUS)