The International Monetary Fund has openly criticised the UK government over its plan for tax cuts, warning that the measures are likely to fuel the cost-of-living crisis.
In an unusually outspoken statement, the IMF said the proposal was likely to increase inequality and add to pressures pushing up prices, reports BBC.
The government says the measures will kickstart economic growth.
On Wednesday morning, sterling fell by 0.7% to $1.06 after the IMF raised its concerns. It comes after the currency hit a record low of around $1.03 on Monday.
Chancellor Kwasi Kwarteng unveiled the country's biggest tax package in 50 years on Friday. But the £45bn cut has sparked fears that government borrowing could surge along with interest rates.
The IMF works to stabilise the global economy and one of its key roles is to act as an early economic warning system.
It said it understood the package aimed to boost growth, but it warned that the cuts could speed up the pace of price rises, which the UK's central bank is trying to bring down.
The IMF said that the government publishing a fiscal plan on 23 November gave it an opportunity to "re-evaluate" tax measures, "especially those that benefit high income earners".
The UK government proposals would scrap the top rate of income tax, and end a cap on bankers' bonuses, among other measures.
The announcement on Friday sparked days of financial turmoil, as investors dumped the pound and UK debt. Some of the country's biggest lenders also suspended mortgage deals amid the uncertainty.
The Treasury said: "We are focused on growing the economy to raise living standards for everyone."
It added that Mr Kwarteng was due to publish his medium-term plan for the economy on 23 November, which would include ensuring that UK debt falls as a share of economic output in the medium term.
Meanwhile, Lord Frost, the former Brexit minister and close ally of Prime Minister Liz Truss, criticised the IMF's statement.
He told the Daily Telegraph: "The IMF has consistently advocated highly conventional economic policies. It is following this approach that has produced years of slow growth and weak productivity.
"The only way forward for Britain is lower taxes, spending restraint, and significant economic reform."
BBC economics editor Faisal Islam says the IMF's "stinging rebuke... reflected similar concerns from the world's major finance ministries that a crisis brewing in the UK could spill over into a global slowdown".
Adnan Mazarei, a former deputy director at the IMF, said it was common for the foundation to make strong statements on "emerging market countries with problematic policies but not often G7 countries".
He said it showed the IMF was worried that tax cuts were permanent and that the budget would have to be financed by more borrowing. It was also concerned about inflation rising which would require interest rate increases by the Bank of England.
He told BBC Radio 4's Today programme "the fear" was the Bank of England and the Treasury were not working together properly for the benefit of the UK economy.
He said: "There is also a sense of problems in the country's economic management and their ability to handle issues, which could lead to problems of inflation [and] financial market difficulties... for example we've seen problems in the mortgage markets which will hurt the UK household."
On Tuesday, the Bank of England signalled that it was prepared to ramp up interest rates in response to the slump in the value of the pound.
Its chief economist Huw Pill said the Bank "cannot be indifferent" to the developments of the past days.
He said the Bank would have to deliver a "significant monetary policy response" to protect sterling.
Speaking to BBC Two's Newsnight, former US Treasury Secretary Larry Summers described the situation facing the UK as "very ominous".
"I can't in all honesty remember a time when a set of policy announcements from a G7 country elicited so negative a response both from markets and from economic experts," he said.
"When a country sees its interest rates rise by [as much as they have] in two days at the same time that its currency is falling in a major way, that is a sign that there has been a major loss of market credibility and market confidence.
"The kind of warning that Britain received from the IMF today is a kind of warning that comes much more frequently to emerging markets with new governments than to a country like Britain."
Asked about the UK's plans at an event in Washington, White House economic adviser Brian Deese said he had not been surprised by the negative reaction of the markets and that it was important to focus on "fiscal prudence, fiscal discipline", the Reuters news agency reported.
Moody's credit rating agency said on Wednesday that the UK's plan for "large unfunded tax cuts" was "credit negative" and would lead to higher, persistent deficits "amid rising borrowing costs [and] a weaker growth outlook". Moody's did not change the UK's credit rating.
Labour's shadow chancellor Rachel Reeves said the government must "urgently lay out how it will fix the problems it created through its reckless decisions to waste money in an untargeted cut in the top rate of tax".
"Waiting until November [when the fiscal plan is published] is not an option," she said. Instead, "the government must urgently review the plans made in their fiscal statement last week".
She added: "This statement from the IMF should set alarm bells ringing in government and make it clear that they need to act now."
IMF statement in full:
"We are closely monitoring recent economic developments in the UK and are engaged with the authorities.
"We understand that the sizable fiscal package announced aims at helping families and businesses deal with the energy shock and at boosting growth via tax cuts and supply measures.
"However, given elevated inflation pressures in many countries, including the UK, we do not recommend large and untargeted fiscal packages at this juncture, as it is important that fiscal policy does not work at cross purposes to monetary policy.
"Furthermore, the nature of the UK measures will likely increase inequality.
"The November 23 budget will present an early opportunity for the UK government to consider ways to provide support that is more targeted and re evaluate the tax measures, especially those that benefit high income earners."