Police recovered the bodies of two youths from a house in Koylar Ghat area of Dhaka's Kamrangirchar on Tuesday morning.
The deceased were identified as Miraj, 20,and his friend Rubel, 18.
Miraj was alone in their house as his parents went to their village home in Munshiganj on Monday, he said.
"Both of the bodies had signs of vomiting. We primarily suspected they ate or drank something and died of poisoning. We will investigate the incident," he added.