The UN has condemned an air strike on a Yemen detention centre that has killed more than 70 people.
The facility in Saada, a stronghold of the rebel Houthi movement in north-western Yemen, was hit on Friday.
In a statement on Saturday, the Saudi-led coalition fighting Houthi rebels in the country denied it had carried out the air strike.
The coalition also said the site was not on a list of targets to avoid that had been agreed with the UN and had not been reported by the Red Cross.
Saudi-led coalition forces have been fighting Houthi rebels since 2015. Tens of thousands of civilians, including more than 10,000 children, have been killed or wounded as a direct result of the fighting.
Millions have been displaced and much of the population stands on the brink of famine.
Hours after the air strike, rescue workers were still pulling bodies out of the rubble, and hopes of finding survivors are fading, says BBC Middle East correspondent Anna Foster.
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Houthi-run television showed pictures from the scene of men clearing debris with their hands and of wounded at a local hospital. MSF said one hospital had received more than 200 casualties.
"There are many bodies still at the scene of the air strike, many missing people," Ahmed Mahat, MSF chief in Yemen, told AFP news agency. "It is impossible to know how many people have been killed. It seems to have been a horrific act of violence.
US Secretary of State Antony Blinken also called for de-escalation.