Coronavirus vaccine: Oxford vaccine failed in animal trials

Sun Online Desk

22nd May, 2020 03:47:24 printer

Coronavirus vaccine: Oxford vaccine failed in animal trials

 

As the world puts a joint effort in battling the novel coronavirus, scientists and medical researchers are also working round the clock to develop a vaccine to defeat the highly infectious disease.

 

What is the Oxford vaccine

 

The World Health Organization has already identified seven to eight top vaccine candidates that are being accelerated and effort is underway to speed up the development of these vaccines.

In this race, the vaccine candidate being developed by Oxford University was touted as one of the leading potential vaccines. For their vaccine candidate ‘ChAdOx1 nCoV-19’, the researchers used a weakened strain of common cold virus (adenovirus) that causes infections in Chimpanzees and combined it with the genetical material of SARS-CoV-2 spike protein.

The vaccine candidate was based on the idea of teaching the body to recognise the spike protein of the novel coronavirus and prepare the immune system to attack it, in case the virus ever entered the body. Additionally, clinical trials of the vaccine had already begun and more than 320 people were already given the jab of ChAdOx1 nCoV-19.

What do the recent reports say

The COVID-19 vaccine being produced by the Oxford University is among the top 8 candidates which are being tested on humans for safety and efficacy, but recent reports have shown that it is only “partially” effective as it was not able to prevent infection in rhesus macaque monkeys. To conduct the trial, six monkeys were vaccinated with the candidate vaccine, while three animals were given ChAdOx1 GFP.

 

 


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