Glasgow's world-renowned School of Art has been gutted by another huge blaze, four years after part of the building was destroyed by fire.
Flames ripped through the celebrated Mackintosh building after it caught fire at around 23:20 BST on Friday.
The blaze has spread to nearby buildings, including the Campus nightclub and O2 ABC music venue, which suffered "extensive damage".
No casualties have been reported, the Scottish Fire and Rescue Service said.
Efforts to bring the fires under control are expected to be "prolonged", Deputy Chief Officer Iain Bushell said.
More than 120 firefighters have been sent to the scene and are faced with "an extremely challenging and complex incident", he added.
The Mackintosh building was badly damaged by fire in May 2014 and was due to re-open next year following a £20 - 35 million restoration project.
Ben, an eyewitness, told the BBC the latest fire looked "much worse" than the previous one.
"This is a blaze, the building is just going up like a tinderbox. It's quite shocking," he said.
Connor Neil, 22, said people were being evacuated from their homes and there was a "big orange light" which could be seen from streets away.