A woman has died after undergoing bee-sting therapy, a form of treatment backed by Gwyneth Paltrow.
The 55-year-old Spanish woman had been having live bee acupuncture for two years when she developed a severe reaction.
She died weeks later of multiple organ failure.
Researchers who studied the case say live bee acupuncture therapy is "unsafe and unadvisable".
It is thought to be the first death due to the treatment of someone who was previously tolerant of the stings.
The woman's case has been reported in the Journal of Investigational Allergology and Clinical Immunology, by doctors from the allergy division of University Hospital, Madrid.
She had been having the treatment once a month for two years at a private clinic to improve muscular contractures and stress.
During a session, she developed wheezing, shortness of breath, and sudden loss of consciousness immediately after a live bee sting.
She was given steroid medication but no adrenaline was available, and it took 30 minutes for an ambulance to arrive.
The woman had no history of any other diseases like asthma or heart disease, or other risk factors, or any previous allergic reactions.