Police have warned drivers of hazardous conditions and thousands of homes in the UK are without power due to snow.
The M1 was blocked at junction 19 after a lorry accident, while police said there had been "multiple collisions" on the A14 in Northamptonshire.
The Met Office has issued warnings for ice in northern Scotland, Northern Ireland and north-east England and snow for Wales and parts of England.
Stansted airport is currently closed as snow is cleared from the runway.
A spokesman for the airport said all flights were suspended and officials did not know when it would be reopened.
Western Power Distribution said 13,000 homes are without power in the East Midlands and West Midlands, with homes in Worcester, Gloucester and Coventry affected.
The firm said the cuts were all snow-related and extra staff - who had been on standby for poor weather - had been called in to work to reconnect properties.
More than 7,000 homes are also without power in the West of England, including 3,400 homes in Wiltshire and more than 3,600 in the Gloucestershire area.
Frank Bird, from Highways England, said the worst of the conditions were now over in the West Midlands, as the bad weather moved eastwards.
He said 2,000 tonnes of salt and grit had been put down in the region overnight, adding that treating roads was a "battle that we are constantly fighting".
One of those caught up in the problems on the A14 was lorry driver Simon Talbot, who told BBC News he had been stuck for three hours.
"I've been stationary since about 02:20 GMT westbound on the A14, there is approximately 5ins (12cm) of snow we've had and I'm just stationary."
He added: "I'm on an incline and there are lorries and vans in front that are unable to get up the hill because of the snow. So it is just a waiting game at the moment."
"Unfortunately, all lanes are currently blocked. Police and Highways are aware and are currently dealing. Please make alternative travel arrangements."
It added: "Please be aware that snow is falling across the county and in some cases it is settling, causing hazardous conditions for drivers. Please take care and take the necessary precautions."
Officers said there are "long delays" on the A34 between the M4 and A4185 in Berkshire due to the weather conditions and slow moving traffic.